![]() Bohr’s physiological and alveolar dead space variables, cardiac output (CO), mean pulmonary pressure (MPP), venous admixture ( Q ˙ s / Q ˙ t ), airway dead space, tidal volume, oxygen consumption, and slope III of the volumetric capnogram were evaluated (explanatory variables). Data to calculate the CO 2 indices (response variables) and dead space variables were measured every 30 min. Six healthy adult horses were anesthetized in dorsal recumbency breathing spontaneously for 3 h. The aim of this experimental study was to evaluate which factors influence these CO 2 indices in anesthetized spontaneously breathing horses. The arterial to end-tidal CO 2 difference (P (a-ET)CO 2) and alveolar dead space fraction (VDalv frac = P (a-ET)CO 2/PaCO 2), are used to estimate Enghoff’s “pulmonary dead space” (V/Q Eng), a factor which is also influenced by venous admixture and other pulmonary perfusion abnormalities and thus is not just a measure of dead space as the name suggests. 5Division of Anaesthesiology, Vetsuisse Faculty, Zurich, Switzerland. ![]()
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